Senin, 12 September 2011

HEALTH MANAGEMENT. Delete old cholesterol way could be used to Unfur of arteries

Called "Self digestion", the cumulative dysfunctional molecules from cells, clears cholesterol an old phone way Autophagy also mobilized and exports and provide for a totally new goal under the direction of the University of Ottawa Heart for drugs "unfur arteries" or reverse atherosclerosis, the main cause of heart attack and stroke, according to the Research Institute (UOHI) in Canada.
Run Director of HDL biology laboratory, UOHI and colleagues from UOHI and Columbia University in New York, United States, found, remained, during the evolution researcher Dr. Yves Marcel, Autophagy, a process that developed and is in single-cell organisms, devours and digested cholesterol which in artery walls has accumulated.
In a statement published yesterday Marcel said 8 September, the press:
"The finding that Autophagy regulated offers also functions to digest and free cholesterol from cells, and the fact that we know that this option will hope for the development of new drugs, enable the export of cholesterol could arteries."
Cholesterol is an important and necessary molecule in mammals, where it produced, hormones and cell membranes and is carried out by the body in the blood. However, it collects in the arteries, that they "fur up" and turn in the atherosclerosis, where narrower and narrower, finally caused blockages and circulation of the heart, which frequently causes heart attacks and strokes reduces arteries,.
Rockefeller Mireille Ouimet, an essential factor in the work, said:
"It is urgently necessary to understand how the accumulation can be reversed by cholesterol in the arteries."
Researchers have discovered that cholesterol accumulation itself raises cholesterol Autophagy, caused, published and broken by the liver, where it is removed from the body be and.
Marcel suggests that perhaps some people with coronary heart disease (CHD) unable to cholesterol in your arteries Autophagy option to delete. A route for new drugs could reactivate this option.
Cell metabolism researchers published details of their work this year in the journal.

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