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Tampilkan postingan dengan label develop. Tampilkan semua postingan
Tampilkan postingan dengan label develop. Tampilkan semua postingan

Rabu, 09 November 2011

Chickenpox Lollipops? Mailing Tainted Suckers So Kids Develop Immunity Is Illegal

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NASHVILLE, Tenn. — Parents fearful of vaccinations are being warned by a federal prosecutor that making a deal with a stranger who promises to mail them lollipops licked by children with chickenpox isn't just a bad idea, it's against the law.

Jerry Martin, U.S. attorney for the Middle District of Tennessee, said he was spurred by reports this week by KPHO-TV in Phoenix and WSMV-TV in Nashville about people turning to Facebook to find lollipops, spit or other items from children who have chickenpox.

“Can you imagine getting a package in the mail from this complete stranger that you know from Facebook because you joined a group, and say here, drink this purported spit from some other kid?” Martin told The Associated Press.Isaac Thomsen, a specialist in pediatric infectious diseases at Vanderbilt Children's Hospital, said it's unlikely the items will succeed in giving other children chickenpox.“If there's a very high load on the virus and shipped very quickly, it's theoretically possible,” he said. “But it's probably not an effective way to transmit it. It typically has to be inhaled.”

But Thomsen warned the lollipops could carry more dangerous viruses, including hepatitis.

Martin said it is a federal crime to send diseases or viruses across state lines, whether through the U.S. Postal Service or private services like FedEx or UPS. Sending the lollipops would be illegal under the same law that makes it illegal to mail contagions like anthrax. He said a conviction could lead to a sentence from less than a year to 20 years in prison.

MORE: 1 in 10 Parents Skip or Delay Vaccines

Martin said the items are sought by parents who don't want to give their children vaccines. He said he could neither confirm nor deny that his office is investigating or seeking charges against anyone.

According to the TV reports, parents have turned to a Facebook group called “Find a Pox Party in Your Area” to link up people looking to share the virus.

One of the Facebook postings from Wendy Werkit of Nashville offered a “fresh batch of pox in Nashville shipping of suckers, spit and Q-tips available tomorrow 50 dollars via PayPal.”

Werkit told WSMV that the money was used to cover the shipping costs of the lollipops had been licked by her children.

MORE: Should Pediatricians 'Fire' Patients Whose Parents Don't Vaccinate?

“They can't get (chickenpox) the normal way anymore of just naturally catching and just naturally getting the immunity for life,” Werkit said.

Thomsen, the Vanderbilt physician, said he was even more concerned by a person in the KPHO report seeking items tainted with measles to avoid a school-required vaccination. Measles has a significant mortality rate, causes more complications and is very infectious compared with chickenpox, he said.

And law enforcement won't take any such cases lightly, Martin said.

“If you are engaged in this type of behavior, you're not only potentially exposing innocent people to dangerous viruses and illnesses and diseases, you're also exposing yourself potentially to federal criminal prosecution,” he said.



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Minggu, 18 September 2011

U.S. to develop chip that tests if a drug is toxic

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WASHINGTON | Fri Sep 16, 2011 3:34pm EDT

WASHINGTON (Reuters) - U.S. government researchers plan to design a chip that can check whether new drugs are toxic before they are tested in people, potentially speeding up the development of new therapies.

The chip would lump together human cells from the liver, heart, muscles and other organs, then diffuse a drug through them. Multiple readouts would then show how different proteins, genes and other compounds in the cells react to the medicine.

"If things are going to fail, you want them to fail early," Dr. Francis Collins, the director of the National Institutes of Health (NIH), told Reuters on Friday. "Now you'll be able to find out much quicker if something isn't going to work."

Collins said a drug's toxicity is one of the most common reasons why promising compounds fail. But animal tests -- the usual method of checking a drug before trying it on humans -- can be misleading.

He said about half of drugs that work in animals may turn out to be toxic for people. And some drugs may in fact work in people even if they fail in animals, meaning potentially important medicines could be rejected.

The project aims to bring together new knowledge from engineering, biology and toxicology.

The cells in the chip will be grouped next to each other so they can interact, much as they would in a human body. The chip will be tested with drugs that are known to be safe, and those that are toxic, to look at how the readouts compare.

The Defense Advanced Research Projects Agency (DARPA) and the NIH will each spend up to $70 million over five years on their own separate programs to develop the chip.

They will also work with the Food and Drug Administration, the U.S. drugs regulator, which could potentially use the chip to test drugs during the approval process.

It takes an average of 15 years and more than $1 billion to get approval to sell a drug in the United States, according to the drug industry group PhRMA.

"We know the development pipeline has bottlenecks in it, and everyone would benefit from fixing them," Collins said.

(Reporting by Anna Yukhananov; editing by Tim Dobbyn)



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