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Sabtu, 29 Oktober 2011

FDA links new blood clots birth control drugs

WASHINGTON (AP) - concerns of security with the popular birth control pill as yaz increased federal Thursday that scientists of Health reported that the drug from Bayer and other newer birth control treatment appear to increase the risk of dangerous blood clots more older drugs.

A new study published by the Food and Drug Administration reviewed the medical history over 800,000 women U.S. takes different forms of control of births between 2001 and 2007. On average, women taking Yaz had 75% more likely to end up with a blood clot than women older birth control medications.

YAZ contains estrogen with a synthetic hormone of next generation called drospirenone, who is known to increase the level of potassium in the blood. FDA compared the medical records of women taking the drug with those who take the old drug levonorgestrel.

YAZ, Yasmin and related pills containing drospirenone of were free of second-best-selling Bayer to $ 1.6 billion in global sales last year.

In 2009, the FDA has taken an unusual step order Bayer to run corrective on Yaz TV advertisements, stating that the ability of drugs exaggerated the drugmaker marketing campaign to prevent acne and premenstrual syndrome.

Bayer Healthcare, a division of the German conglomerate, it says "currently assessing this publication and cannot comment on at this time."

The Agency also reported complications higher in women using the Ortho Evra of Johnson & Johnson and ring patch vaginal Nuvaring of Merck & Co. Inc. These drugs combine estrogen, which is present in all birth control pills, with two other synthetic hormones in the last decade.

The FDA said it has not reached a final conclusion on the safety of the drugs but will hold a meeting with scientific advisors on 8 December.

The consumer safety advocates have criticized the Agency of the latest and most expensive birth control drug approval when cheaper, generic medicines with established security records are widely available.

"At some point we must ask why the FDA continues to approve drugs that are less safe and have no advantage over drugs already on the market," said Dr. Diana Zuckerman, President of the National Centre for women and families, a group of consumers for women's health issues. "With all these different birth control options, why take the more expensive that can kill you?"

Recent studies have reached different conclusions about the risks of contraceptive pills more recent.

A study published earlier this week on more than 1 million Danish women found that women taking Yaz and other newer drugs have twice the risk of blood clots as women taking the hormone levonorgestrel older. The findings published Tuesday in the British Medical Journal.

However, two studies published in 2007, conducted as part of the regulators FDA postmarketing requirements or European, have not found any difference in clotting between comparable groups.

Pills of birth control containing drospirenone include Yaz, Yasmin, Bayer's Beyaz, Safyral; Sandoz Syeda and Loryna; as well as Ocella Barr, Watson Pharmaceuticals Zarah and Loryna of Teva Pharmaceuticals laboratories.

Associated Press

Technology



News

Senin, 10 Oktober 2011

To Save Wildlife, Namibia's Farmers Take Control

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October 10, 2011

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In a radical experiment, Namibia turns its wildlife over to its farmers

It's dawn and 40 degrees out. The air tastes of dust. Elias Neftali is behind the wheel of a truck, driving us through a long valley encircled by red-rock mountains. As a farmhand in the northwest desert of Namibia, Neftali used to shoot wild animals trying to eat his livestock.

Now he protects wild animals. And that can be scary.

"Oh my god, yep," he says. He tells me about a night he was sleeping in a bungalow out in the bush with some other wildlife guards.

He heard somebody screaming. "When I opened my eyes it was this elephant," Neftali says. "He was so big, standing there, he could see us. All I did was to like, fall to my feet. And he hit the bungalow somewhere in the roof. The things that you see in movies. We can hear him breathing so heavy, like very angry."

Everybody froze. The elephant paused, then turned to the next building.

"He threw off that roof completely. He took out all the toilets." After trashing the building, the elephant turned and left.

I ask Neftali why he's willing to risk his life to be a wildlife manager. "I love it," he says simply, "to be in nature."

There are others like Neftali, people who have left raising livestock to participate in a radical experiment in Namibia: helping wildlife survive by putting their fate in the hands of the people who share their lands. It's as though the U.S. government said to the people who live around Yellowstone National Park, "You know what? All those wild animals in the park — the grizzlies, the bison, the wolves — they belong to you."

A Village Council For Wildlife

In the mid-'90s, the Namibian government did that. Mostly in the arid northwest, farmers and others who lived from the land were allowed to form "communal conservancies."

These are like village councils. They wield control over the wildlife within the conservancy boundaries, which are set by conservancy members and the central government. Conservancies then partner with tourist lodges and safari companies and take a cut of the income from tourists who come to see the giraffes, zebras, lions, rhinoceroses and other exotic animals. They operate campsites, too. And they collect thousands of dollars from trophy hunters who come to shoot lions and cheetahs and antelopes. A single lion can bring in up to $10,000.

A group of Khoadi-Hoas conservancy members meet over morning tea at the Hoada campsite in northwestern Namibia. Enlarge John W. Poole/NPR

A group of Khoadi-Hoas conservancy members meet over morning tea at the Hoada campsite in northwestern Namibia.

A group of Khoadi-Hoas conservancy members meet over morning tea at the Hoada campsite in northwestern Namibia. John W. Poole/NPR A group of Khoadi-Hoas conservancy members meet over morning tea at the Hoada campsite in northwestern Namibia.

Since the conservancies started in 1998, they've collected nearly $27 million in gross income, in a country where rural families live on a few dollars a day.

As a result, poaching has been nearly wiped out in Namibia, and wildlife numbers are rising. Meanwhile, across Africa, wildlife numbers are declining as human populations chip away at habitat and poaching increases for bush meat and black market items like rhino horns.

But living with wildlife — and profiting from it — hasn't been easy. Especially when most of the time, a rural Namibian's first instinct may be to protect his or her livestock.

Damage Control

A few days after my truck ride with Neftali, I'm in the Khoadi-Hoas conservancy, riding in a donkey cart with Albert Gureseb.

The conservancy is a little bit smaller than Rhode Island; about 3,200 people live within its boundaries.

Gureseb got his first job with Khoadi-Hoas as a hunting guide. These days, he handles damage control .

Every week or so, Gureseb makes the rounds of local farms, looking for farmers who have lost livestock to predators. This is the price of success: Wildlife roams freely around across the conservancies. And that means around the farmers. There's no fence or buffer zone to keep people, livestock and predators away from each other.

"When the conservancy started, the number of predators increased because we were looking after them," says Gureseb. "That did not make people happy."

Rural conservancy residents rely on donkey carts to move materials around the vast expanses of northwest Namibia. Enlarge John W. Poole/NPR

Rural conservancy residents rely on donkey carts to move materials around the vast expanses of northwest Namibia.

Rural conservancy residents rely on donkey carts to move materials around the vast expanses of northwest Namibia. John W. Poole/NPR Rural conservancy residents rely on donkey carts to move materials around the vast expanses of northwest Namibia.

We visit a one-room farmhouse on a dusty hill. Goats shuffle behind a wire fence. Katrina Katatumosa lives here with her daughter. As she tends an open fire under a pot of beans, she says a cheetah ate three of her goats just the other night. She stood by, helpless.

Katatumosa complains that the conservancy doesn't pay the full market value of her goats. Even if they did, she says, she still would want the cheetahs dead.

Gureseb smiles. He says he understands but reminds her that outside the conservancies, farmers get nothing at all when a predator kills livestock. He agrees that it would be good to pay more, but the money just isn't there. The head of the Khoadi-Hoas conservancy, Hilga Howeses, says they ran through half their budget for reimbursing farmers for livestock in the first three months of the year. "We are doing better now," she says of the 13-year old conservancy, but she adds, "the biggest challenge is human-wildlife conflict."

Farther down a dirt road, I meet Michael Guiseb at his uncle's farm. A few days before, an elephant came through and almost destroyed his cistern, a concrete tank 15 feet high.

Elephants hunt water. To try to cut down on these human-animal conflicts, the conservancy is building them water wells, away from the farms. Guiseb says that's good. The wildlife had to adapt to people, he says. Now people must learn to adapt to wildlife.

"Some people want to kill the elephants," says Guiseb, who is studying conservation. "But the good way is, let's conserve it. Bringing them closer to the wildlife, to the elephants, will change the attitude of the people."

Stolen Lands, Stolen Rights

Most conservancy members I talked to say profiting from wildlife is better than when the white apartheid government owned it all.

The modern country of Namibia started to coalesce in the late 19th century. Early German colonizers swindled large tracts of land from the indigenous people. In 1884, Germany took control of the area, calling the new colony South West Africa.

Over the next few years, the indigenous people fought back. At least 65,000 Herero, one of the dominant groups living in the area, were killed in the uprisings.

The Germans did recognize the value of the land and its wildlife, though. They set up what was the largest game reserve in the world at the time, in the rugged Kaokoveld region of the northwest. It covered an area the size of Maine, and was home to many native groups as well as some of Africa's most famous wildlife: rhinos, lions, elephants, giraffes and cheetahs.

Germany lost the colony in a battle with South Africa in the middle of World War I. Over the next few decades, native populations lost even more rights under the apartheid South African government.

In 1967, the government gave white landowners formal ownership of game on their land. Many of the animals living on rural communal lands were shipped away to a newly established national park for protection — part of the new "fortress conservation" movement taking hold in Africa.

In 2009, the Namibian conservancy received more than $9 million in funding from government and NGO sources. The system earned over $4 million from tourism-related activities. Conservancies on a whole spent nearly $4 million in 2009.

Namibian Conservancy Money Flow, 2009

'Arid Eden' Under Duress

Garth Owen-Smith was a young South African who moved to the Kaokoveld around this time. He found herdsmen and the wildlife under an increasing strain.

When Owen-Smith came to the Kaokoveld, it was an area under increasing duress — for farmers and for wildlife. In 1966, the United Nations had ordered South Africa out of the newly named Namibia, but the apartheid regime tightened its hold instead, and soon after a war for independence erupted.

In 1970, the South African government de-proclaimed the large Kaokoveld reserve established under the Germans and started carving it up into designated "homelands" for indigenous people. The majority of the country's population was pushed onto just 40 percent of the land.

Most native families were given too little land to make a living from either farming or ranching, so for many poaching was a necessary evil. At the same time that white government officials took sport hunting trips onto the smaller game reserves, native poachers were often subject to brutal treatment if caught.

"It was a disastrous situation," Owen-Smith recalls. "Black people were alienated. Wildlife was for the elites, whites only."

War broke out in the country. Poaching by soldiers and by rural farmers was rampant. Life was hand to mouth. Many species were on the edge of extinction there.

It's hard to imagine this from where Owen-Smith now sits — at his desert oasis, a compound of stone bungalows shaded by trees, called "World's End." He lives here part of the year with his partner, Margaret Jacobsohn. World's End has also become a hub for conservancy meetings, where members camp for days to talk business, compare notes and learn everything from wildlife management to accounting.

Conservation leader Garth Owen-Smith now lives at a remote environmental station in the Kunene (Kaokoveld) region of northwest Namibia. Enlarge John W. Poole/NPR

Conservation leader Garth Owen-Smith now lives at a remote environmental station in the Kunene (Kaokoveld) region of northwest Namibia.

Conservation leader Garth Owen-Smith now lives at a remote environmental station in the Kunene (Kaokoveld) region of northwest Namibia. John W. Poole/NPR Conservation leader Garth Owen-Smith now lives at a remote environmental station in the Kunene (Kaokoveld) region of northwest Namibia.

"Game used to be very important for rural people," Owen-Smith says. "For meat, for skins and for trade. But with colonialism, wildlife became state property, and for any local person to hunt was poaching, and he could go to jail. It was almost a Robin Hood syndrome."

"There was no future in this for Africa," he says. For wildlife to survive, it had to once again have meaning for the rural people who lived around it.

'They Wanted The Ownership Back'

Owen-Smith and local conservationists organized themselves into a nongovernmental organization called Integrated Rural Development and Nature Conservation, or IRDNC. They reached out to the Herero headmen, asking them to figure out a way to stop the poaching.

"It was as much their idea as ours," Owen-Smith recalls. "They did not want to see the game wiped out. But as it belonged to the government, they said, 'Well, that's the government's responsibility to stop the hunting.' "

That wasn't going to happen, he says. At the time, there were two government workers sharing one vehicle to patrol an area of 25 million acres.

Paying the local people to stop poaching wasn't going to work either.

"That is the key that is often forgotten," says Owen-Smith. "People think if they are getting financial benefit from something, it will change the way they think. That may be how Westerners think. But out there, there was a real hostility to conservation, for the fact that a valuable resource had been taken away from them and they wanted the ownership back of that resource."

Owen-Smith and the headmen decided to enforce a de facto ownership. The traditional leaders appointed their own game guards. The headmen knew who in the community was reliable, and they knew who could find the poachers: people who were poachers themselves. Turning poachers into game guards worked.

"They were able to stop the poaching within a few years, and we haven't looked back."

'Wildlife Would Be Our Gold'

By the time Namibia won its independence from South Africa in 1990, wildlife had rebounded under the game guard system. The next step was to organize this loose confederation of game guards and have the system officially recognized by the government.

Rural people organized committees to sign up members and manage wildlife on a wider scale. Margaret Jacobsohn is Owen-Smith's partner and an anthropologist who has lived in Namibia for 27 years.

"There was a vision that one day wildlife would be our gold," she told me. "That it would be more valuable alive than in cooking pots."

International conservation and development organizations took note. Starting in 1992, the World Wildlife Fund and USAID invested nearly $17 million to help launch the conservancy system.

A young elephant sprays sand on his back to keep the midday sun off, or maybe for fun, in Twyfelfontein conservancy. Enlarge John W. Poole/NPR

A young elephant sprays sand on his back to keep the midday sun off, or maybe for fun, in Twyfelfontein conservancy.

A young elephant sprays sand on his back to keep the midday sun off, or maybe for fun, in Twyfelfontein conservancy. John W. Poole/NPR A young elephant sprays sand on his back to keep the midday sun off, or maybe for fun, in Twyfelfontein conservancy.

"In these sorts of areas, with very low populations, wildlife is actually a better form of land use than livestock farming," says WWF-Namibia's Greg Stuart-Hill. "Livestock farming generates one or two cattle herders, or goat herders, whereas the wildlife industry generates a broad cross section of economic opportunities."

In 1996, the multiracial government passed legislation that gave back to black Namibians the right to manage their wildlife. The legislation set up terms for how to create and register a communal conservancy and how to become eligible to receive financial aid and guidance from international donors and NGOs.

In the wake of this legislation, rural groups were lining up in the nation's capital of Windhoek to set up conservancies. By 2011, communities had banded together to form 64 conservancies.

Numbers for many species, including the endangered black rhino, are now strong and holding steady. Rhinos are up from about six in the northwest in the early '80s to more than 1,400. Cheetahs have gone from 2,000 in the 1980s to 4,000 today. In 1995, there were about 7,500 elephants in Namibia. Today, there are at least 16,000. The conservancy system isn't entirely responsible, but it is a big part of a government-supported, nationwide conservation effort.

Lions are back, too. According to Chris Weaver, head of World Wildlife Fund-Namibia, in 1995 lions numbered fewer than 20 in northwest Namibia. Today, the population is closer to 125.

Away From Tourists

On a drive through the red desert and scrub of the Torra Conservancy in the northwestern region of Kunene, we spot a thicket of green at the end of a dirt track, which means a spring. And where there's water in Kunene, there's usually a bush camp.

A male steenbok peers from behind a veil of grass in Twyfelfontein conservancy. Enlarge John W. Poole/NPR

A male steenbok peers from behind a veil of grass in Twyfelfontein conservancy.

A male steenbok peers from behind a veil of grass in Twyfelfontein conservancy. John W. Poole/NPR A male steenbok peers from behind a veil of grass in Twyfelfontein conservancy.

Hunters in camouflage sit around a fire drinking coffee from metal cups. Among them is Dirk Nesenberend. He owns a gun shop in Windhoek, the capital.

"I grew up shooting and hunting from an early age," he tells me. He's carrying a .280 Remington, which can bring down an antelope at 300 yards in the right conditions.

"Shoot for the brain," he says. It's quickest and most humane.

Nesenberend and the other hunters put noise suppressors on their rifles. If they don't, game will scatter after the first shot. Moreover, they'll learn to associate vehicles and people with being shot, and run away at first sight. That would be bad for the tourism industry.

"Tourists, if they come here and not see any animals, it's not going to be a successful tourism industry," Nesenberend says.

The hunters aren't here as paying guests. They've been invited by the Torra Conservancy to help cull herds and provide bush meat for conservancy members.

Torra is just southwest of Khoadi-Hoas. The two are among the oldest conservancies, established in 1998 and currently involving a combined 4,400 members..

Hunt leader Richard Fryer directs the team down a back road, out of the sight of safari vans full of tourists. His bull terrier, Jesse, sits next to the gearshift, panting with excitement. He likes the hunt. Fryer once was a soldier. Now he's a wildlife manager with the IRDNC, the NGO founded by Owen-Smith.

Spooked by a noise, giraffes in northwest Namibia interrupt lunch to look around. Enlarge John W. Poole/NPR

Spooked by a noise, giraffes in northwest Namibia interrupt lunch to look around.

Spooked by a noise, giraffes in northwest Namibia interrupt lunch to look around. John W. Poole/NPR Spooked by a noise, giraffes in northwest Namibia interrupt lunch to look around.

We soon find a herd of springbok: deerlike, though a bit smaller. Known for their bounding leaps as they run, they're tan and white, with curved horns, almost heart-shaped. It's been a wet year; the springbok are grazing on tall green grass.

Fryer calculates the distance to the target through binoculars. At 248 yards, the shooter fires a shot. Then another.

"They're good," Fryer says of the hunters. Conservancy members here tried to do a big cull but it didn't work well. "You've got to have the right equipment, the right rifle, a good scope."

These rifles cost thousands of dollars. Each bullet costs a couple of U.S. dollars. With a cull of 230 animals, those costs are almost prohibitive for conservancies still very much struggling to make ends meet. The hunters donate their time, and supply their own equipment, in exchange for the opportunity to hunt.

We walk up a rocky hill to retrieve the dead animals. Each springbok provides about 30 pounds of meat. Young men from the conservancy haul the two animals to the truck and load them in the back.

Later in the afternoon at a nearby farm, young men hang the day's kill from hooks and begin the butchering. They'll deliver the meat to local farmers. About 40 percent of conservancy members are eligible for free bush meat in northwest Namibia.

The conservancies also allow trophy hunting for lions, cheetahs, elephants and other big animals. It's the second-biggest source of income for conservancies, after tourist lodges. Trophy hunting brought in nearly $700,000 of the roughly $4 million a year the conservancy program made as a whole in 2009.

All of this hunting raises hackles among those who see wildlife as something only to look at and photograph. But not for Owen-Smith.

Sitting in the shade of his bungalow at World's End, he says conservationists can be naive. "A lot of conservationists are actually protectionists. They see wildlife as some elevated animals." He says that goes for tourists as well.

"The perception in the eyes of many tourists and usually urban people is that wildlife is something sacred. We don't mind cattle being killed, or sheep or goats being killed, but you can't kill wildlife. Which is a nonsensical perception."

Beyond Money: 'This Thing Is Ours'

Living with animals and profiting is a thorny business, but it's working in Namibia. As wildlife numbers decrease across Africa, they're flourishing here.

Namibia is one of the most sparsely populated countries in Africa, with 2 million people living in an area comparable to Louisiana and Texas combined. People and animals here don't compete for land the way they do in Kenya, for example. Nonetheless, it's still a poor country, with few natural resources beyond its wildlife and rugged beauty. And it has few avenues of economic opportunity and development for its people.

The conservancies still receive about $10 million a year in support, but at an individual level, 21 are now self-financing. They make enough money from tourism, trophy hunting and handicrafts to cover their costs and even provide social benefits such as HIV/AIDS care.

"More and more communities are wanting to join this conservancy program," says Stuart-Hill of WWF-Namibia. "We no longer have to go out and try and convince people that wildlife is a good opportunity. They're knocking on the doors, they're knocking constantly, looking to organize themselves, register conservancies. I think it's started a big movement."

The prehistoric rock drawings at Twyfelfontein, a UNESCO World Heritage Site, reflects the ancient relationship between indigenous peoples and wildlife. Enlarge John W. Poole/NPR

The prehistoric rock drawings at Twyfelfontein, a UNESCO World Heritage Site, reflects the ancient relationship between indigenous peoples and wildlife.

The prehistoric rock drawings at Twyfelfontein, a UNESCO World Heritage Site, reflects the ancient relationship between indigenous peoples and wildlife. John W. Poole/NPR

The prehistoric rock drawings at Twyfelfontein, a UNESCO World Heritage Site, reflects the ancient relationship between indigenous peoples and wildlife.

Owen-Smith retired last year from IRDNC, handing it over to John Kasaona, son of one of the first poachers turned game guards.

Kasaona says conservancies mean more than income for poor farmers. "People are making decisions. The same decisions they would make on their own livestock, they are making it on wildlife. So it gives them a sense of ownership — 'This thing is ours. We are proud of it.' It ensures that it will support you for as long as you are on this planet."

The whole system has been a steep learning curve for rural people as they transform from subsistence farmers to small-business owners. Some conservancies are failing — not all are rich in wildlife. But the success of others shows that wilderness in Africa can pay its own way, and more.

"We have got open landscape, still not occupied by human beings," Kasaona says. "If we don't look after the resources, I don't know how Africa is to support its citizens."



Health Management



Education Information

Rabu, 28 September 2011

Asthma tied to poorer diabetes control in kids

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By Amy Norton

NEW YORK | Mon Sep 26, 2011 2:16pm EDT

NEW YORK (Reuters Health) - Kids with diabetes may have a higher-than-average rate of asthma, and those with both conditions seem to have a tougher time keeping their blood sugar under control, a study out Monday suggests.

Researchers found that among 2,000 3- to 21-year-olds with diabetes, 11 percent had asthma -- higher than the roughly 9 percent rate among children and young adults in the U.S.

The difference was bigger when the researchers looked at the 311 young people with type 2 diabetes, the form associated with obesity and usually diagnosed in adults.

In that group, 16 percent had asthma, compared with 10 percent of those with type 1 diabetes.

Type 1 diabetes is caused by an abnormal immune system reaction that kills off the pancreatic cells that make insulin, a hormone that helps shuttle sugar from the blood and into body cells to be used for energy. People with the disease have to take shots of synthetic insulin (or use an insulin pump) every day to keep their blood sugar levels normalized.

In this study, kids with both type 1 diabetes and asthma were more likely to have poor blood sugar control than their peers who were asthma-free: 15.5 percent, versus 9 percent.

"Poor" blood sugar control meant having a hemoglobin A1C level of more than 9.5 percent. Hemoglobin A1C is a measure of long-term blood sugar control, and experts say it should be kept below 7 percent in adults, while children's can go as high as 8.5 percent depending on their age.

The reasons for the findings, which appear in the journal Pediatrics, are not completely clear.

But the higher rate of asthma among young people with type 2 diabetes suggests a role for obesity, according to lead researcher Mary Helen Black, of the department of research and evaluation at Kaiser Permanente Southern California.

"It's pretty well-established that there's an obesity-asthma connection," Black told Reuters Health in an interview.

As for why young people with type 1 diabetes and asthma had poorer blood sugar control, one possibility is that there is a "real biological connection," Black said.

Some past research, for example, has found that people with poorly controlled diabetes are more likely to show dips in lung function over time than those with well-controlled diabetes. But the reasons for that are unknown.

On the other hand, Black said, it may simply be tougher for kids with type 1 diabetes to control their blood sugar when they have another chronic health problem.

"It can be incredibly challenging to manage both conditions," Black said.

The researchers did find that when kids with both diseases were on asthma medication, their blood sugar control was better.

In particular, poor blood sugar control was seen in less than 5 percent of those taking asthma drugs called leukotriene modifiers (sold under the brand-names Singulair, Accolate and Zyflo).

That compared with about 30 percent of type 1 diabetics who were not on medication for their asthma.

The researchers are not sure if that means there's an effect of the asthma drugs themselves. It may just be that kids with better-controlled asthma are also more likely to have well-controlled diabetes, according to Black.

She said the bottom line for doctors and parents is to be aware that kids with diabetes may have a somewhat higher rate of asthma -- and that those with both may have more trouble with blood sugar control.

If parents notice potential signs of asthma -- like wheezing, coughing or breathing problems that are not related to a cold or other infection -- they should talk to their child's doctor, Black said.

SOURCE: bit.ly/pTAIqi Pediatrics, online September 26, 2011.



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Peliculas Online

Jumat, 23 September 2011

Could Taking Birth Control Pills Make Women's Memory More Like Men's?

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A new study shows that taking birth control pills can affect women's memory.

Shawn Nielsen, a graduate student in neurobiology and behavior at the University of California, Irvine, conducted a study with 66 female students, half of whom were taking oral contraception and half who were not.

The participants were given a unique memory test. Some women were randomly assigned to view an emotionally charged video about a young boy who was hit by a car while walking with his mother and then rushed to the hospital, where doctors reattach his severed feet. Other women watched a more neutral narrative in which the mother and son observe a minor accident and then go to the hospital to practice a disaster drill.

Nielsen, who is working toward her doctorate in the lab of Larry Cahill, a well-known hormone researcher, was interested in teasing apart how differences in estrogen and progesterone levels may affect memory. Previous research has hinted that estrogen may enhance verbal memory; in one study, for example, women taking oral contraception showed better recall of words on the active hormone days of their pill cycle than on days when they either weren't supposed to take active pills or took non-hormonal substitutes.

In the current study, when women who viewed the emotional video were tested a week later about what they saw, those who were taking the pill were able to recall the general thread of the story better than its specific details. This is similar to how men remember emotional events, says Nielsen.

"If we reduce women's sex hormone levels, the change in the type of information they recall is more like what a male participant might remember," she says. The pill works by flattening out natural spikes in estrogen and progesterone — which is what triggers ovulation — and signals the body not to make additional hormones, keeping levels low throughout the cycle.

The results were the exact opposite for the women who weren't on the pill: they were better at remembering details, such as what color shirt the boy had on, whether the mother wore glasses, or whether there was a fire hydrant at the intersection. The naturally cycling women couldn't recall the general narrative of the story as well as they could these details.

This doesn't mean that the pill squelches memory or that it robs women of their ability to recall salient things. It's just a matter of what type of information they remember. Since the pill keeps hormone levels steady throughout the cycle, women who take it tend to react differently to emotionally charged experiences, compared with women undergoing the natural monthly ebb and flow of hormones. And that's important since many of the mental illnesses that affect women — such as depression, anxiety and post-traumatic stress disorder — are extremely emotional in nature.

"What is important about these findings is that sex hormones affect the type of information recalled from an emotional event," says Nielsen. "What that says to us is that these changes are a powerful tool for future studies investigating the underlying neurobiology of these disorders.

"Simply taking the pill and suppressing natural sex hormone levels can affect what type of information you remember from an emotional event. That speaks to the role that estrogen and progesterone play in memory — they affect how a woman remembers an emotional event in her life," says Nielsen.

A better understanding of this connection could lead to more effective therapies that may target such hormonal drivers. Nielsen is already trying to figure out exactly what levels of hormones are associated with changes in recall. She is about to launch additional studies to correlate fluctuating levels of estrogen and progesterone in naturally cycling women with changes in the type of information they recall from emotional events.

The current study was published in the journal Neurobiology of Learning and Memory.

Alice Park is a writer at TIME. Find her on Twitter at @aliceparkny. You can also continue the discussion on TIME's Facebook page and on Twitter at @TIME.



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Peliculas Online

Senin, 19 September 2011

Qualitest recalls birth control pills: FDA

AppId is over the quota
AppId is over the quota

WASHINGTON | Fri Sep 16, 2011 6:10pm EDT

WASHINGTON (Reuters) - Qualitest Pharmaceuticals is voluntarily recalling several lots of birth control pills because of a packaging error that could leave women at risk for unplanned pregnancy, the U.S. Food and Drug Administration (FDA) said.

Select blisters were rotated 180 degrees within the card, reversing the weekly tablet orientation and making the lot number and expiration date no longer visible, the FDA said in a statement on its website.

The error means the daily regimen for the oral contraceptives may be incorrect and could leave women at risk of an unplanned pregnancy, it said. The defects do not pose any immediate health risks.

"This packaging error and the potential for this error to have affected other oral contraceptive products resulted in the company issuing the recall of multiple lots," the agency said.

The recall takes effect immediately. It includes Cyclafem 7/7/7, Cyclafem 1/35, Emoquette, Gildess FE 1.5/30, Gildess FE 1/20, Orsythia, Previfem and Tri-Previfem.

The affected lot numbers can be found here

Qualitest is a unit of Endo Pharmaceuticals Holdings Inc.

(This story corrects the link to affected lot numbers)



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Peliculas Online

Minggu, 18 September 2011

Qualitest recalls birth control pills: FDA

AppId is over the quota
AppId is over the quota

WASHINGTON | Fri Sep 16, 2011 6:10pm EDT

WASHINGTON (Reuters) - Qualitest Pharmaceuticals is voluntarily recalling several lots of birth control pills because of a packaging error that could leave women at risk for unplanned pregnancy, the U.S. Food and Drug Administration (FDA) said.

Select blisters were rotated 180 degrees within the card, reversing the weekly tablet orientation and making the lot number and expiration date no longer visible, the FDA said in a statement on its website.

The error means the daily regimen for the oral contraceptives may be incorrect and could leave women at risk of an unplanned pregnancy, it said. The defects do not pose any immediate health risks.

"This packaging error and the potential for this error to have affected other oral contraceptive products resulted in the company issuing the recall of multiple lots," the agency said.

The recall takes effect immediately. It includes Cyclafem 7/7/7, Cyclafem 1/35, Emoquette, Gildess FE 1.5/30, Gildess FE 1/20, Orsythia, Previfem and Tri-Previfem.

The affected lot numbers can be found here

Qualitest is a unit of Endo Pharmaceuticals Holdings Inc.

(This story corrects the link to affected lot numbers)



View the original article here



Peliculas Online

Selasa, 13 September 2011

HEALTH MANAGEMENT. Researchers examine more recent and secure birth control method

Oregon Health & Science University researchers have discovered a new contraceptive, which is better, more secure and thus a larger population of women available. The research found the OHSU Oregon National Primate Research Center. It is published online in the journal Endocrinology.
Today's birth control methods are several decades old. The food and drug approved administration, for example, "the pill", 1961. It prevents contraception due to increase in the hormone levels of synthetic hormones. This higher hormone levels interrupt the normal menstrual cycle. In short, the synthetic hormones inhibit the release of hormones, responsible for triggering ovulation.
"While the method works, it its disadvantages", said ONPRC scientist Jon Hennebold, PhD. "The main concern is that through a stronger hormone levels, this contraceptive method affects systems in the body of a woman." "Therefore, there are some risks associated with current contraceptive methods, especially heart-cardiovascular disease."
An additional drawback is that hormonal treatments such as the pill of the user of schedule must comply with drugs. Due to this requirement the pill is only about 80 to 90 percent effective.
In contrast, the contraceptive are OHSU researchers develop, is not hormonal and more focused on mechanisms that directly lead the release an egg. This new approach is aimed at the major enzymes responsible for the release of an egg. Hennebold and his colleagues were able to determine exactly what enzymes to focus through the study of rhesus monkeys, which have a very similar reproductive system to humans.
This research in monkeys showed that on these enzymes the release of an egg from the ovary can prevent. The next step for Hennebold and colleagues is the delivery method to determine such drugs and the schedule for drugs.
"Our hope is that the next generation of birth control is targeted and more effective has" Hennebold added. "Much more work is necessary our proposed solution, further, but we believe that better, safe contraceptives are possible."