HEALTH MANAGEMENT. Chemotherapy is so effectively before as after surgery of breast cancer

Whether chemotherapy will not affect long-term local regional results, before or after breast conservation therapy (BCT) what success should more biological factors as chemotherapy timing, according to a study by researchers of the University of Texas MD Anderson Cancer Center. HEALTH MANAGEMENT

Today presenting at the 2011 Breast Cancer Symposium, the study also found that that neoadjuvant chemotherapy (before specific surgery) often shrinking cancer breast tumors, so they probably treatable with BCT or a Lumpectomy, a part of the chest, followed by radiation to remove. TESCO HEALTH INSURANCE

"Even women with clinical stage 2 or 3 breast cancer can have good results with BCT after chemotherapy and do not need a mastectomy," said Elizabeth Ann Mittendorf, m.d., Assistant Professor in the Department of surgical oncology and principal author of the study. "The molecular characteristics of the tumour and other factors have impact on the success, but not in the order, are specified in the chemotherapy and surgery."
The retrospective study of almost 3,000 women treated breast cancer at the MD Anderson from 1987 to 2005 confirmed several previous studies which show that BCT offers high of cancer control for certain patients. HEALTH INFORMATION TECHNOLOGY

Approaches have similar results
Patients examined which only 78 percent surgery before chemotherapy and 22 percent received chemotherapy. Overall, women with more cancer, more adverse prognostic factors that tended to be treated first with chemotherapy. WPA HEALTH INSURANCE

Five and 10 years local regional recurrence time prices were very good for both groups: 97% and 94% and for those, the operation before chemotherapy, 93 percent and 90 percent were for patients, the first chemotherapy.

Mittendorf said, that if malicious features, such as stage and grade of the cancer, age of patient and tumor hormone expression, in were taken into account, the same survival rates primarily for both groups of women.
Neoadjuvant therapy of to complete pathological response when 20% of patients and cancer stage in almost half of the patients that increase stage 2 or 3 cancer before chemotherapy, reduced the likelihood that BCT can effectively for many women after chemotherapy. AHM HEALTH INSURANCE

Book value results forward
"This study shows that women according to selected for BCT, even some women with breast cancer of phase 3, excellent rates of local regional control can have," said Mittendorf. "The most important is made all the factors, to determine the most benefit from this approach can."
The Group intends to expand the M.D. Anderson study patients are handled after 2005.
"Since 2005 treatment techniques have improved, including the ability to add targeted therapies to chemotherapy," she said. "In the future are looking at the effects of the newer agents, and we expect that the results will be even more convenient for women to receive these treatments before the operation."

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